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July 22, 2025
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Orioles at Guardians MLB Betting Preview

Game Time: 7/22, 06:40 PM

1. Brief Intro

The Baltimore Orioles travel to Cleveland to face the Guardians in what promises to be an intriguing matchup. According to DraftKings, the Guardians are favored at -148, while the Orioles are +122 underdogs, with a significant 81% of the money backing the home team. With both teams bringing unique strengths and weaknesses, this game could offer some interesting betting angles.

2. Pitcher Breakdown

Pitching Matchup: Brandon Young vs. Joey Cantillo
Brandon Young (BAL):

Young's pitch arsenal includes a Four-Seam Fastball (44% usage, 93.6 mph), Splitter (19% usage, 87.1 mph), Curveball (17% usage, 76.5 mph), Cutter (12% usage, 86.0 mph), and Changeup (8% usage, 87.4 mph). As a velocity-focused pitcher, Young will look to utilize his fastball to overpower hitters. However, the Cleveland lineup, known for its batting prowess, averages .254 against similar pitch arsenals, suggesting a potential challenge for Young.

Joey Cantillo (CLE):

Cantillo offers a Four-Seam Fastball (40% usage, 91.7 mph), a Changeup (35% usage, 78.0 mph), Curveball (17% usage, 76.5 mph), and Slider (8% usage, 84.8 mph). With a balanced mix of pitches, Cantillo can keep batters guessing. The Baltimore lineup has struggled this season, with an average of .228 against similar pitch types, indicating possible dominance from Cantillo on the mound.

3. Lineup Advantage vs. Arsenal

Lineup Matchups & Batting Edges
For Away Team vs. Home Pitcher:

The Orioles lineup averages .236 this season but projects to .228 against Cantillo's arsenal. The batter with the biggest change is Coby Mayo: Season BA .195 → xBA vs. arsenal .226 (+31 points), Season K% 25.0% → Arsenal K% 22.4% (-2.6%).

For Home Team vs. Away Pitcher:

The Guardians' lineup averages .242 this season but projects to .255 against Young's pitch mix. Daniel Schneemann shows the largest improvement: Season BA .212 → xBA vs. arsenal .279 (+67 points), Season K% 24.9% → Arsenal K% 19.9% (-5.0%).

4. Lineup Strikeout Trends vs. Arsenal

Strikeout Risks & Rewards

The Orioles' projected K-rate is 27.4% vs. Cantillo — up 2.2% from their 25.2% season average, indicating potential strikeout prop opportunities. Meanwhile, the Guardians' projected K-rate is 20.7% vs. Young, increasing by 2.8% from their 18.0% season average, which suggests a less significant strikeout risk.

5. Umpire Influence

Behind the Plate: TBA

Umpire assignment has not been announced, which makes prop volatility a concern. Without specific umpire tendencies, bettors should be cautious of unexpected shifts in strikeout or walk rates.

6. Betting Interpretation / Final Lean

Final Lean & Betting Takeaway

STEP-BY-STEP BETTING ANALYSIS:

STEP 1: Check ALL individual batters for prop opportunities
No batter in the Orioles lineup meets the criteria of xBA > 0.300 with a boost of more than +20 points. However, Daniel Schneemann from the Guardians stands out with an xBA of .279 against Young’s arsenal, boasting a +67 point increase, though still below the .300 threshold.

STEP 2: Check team strikeout rates for pitcher props
The Orioles' projected K-rate against Cantillo is 27.4%, which is above the 25% threshold, but the increase is only 2.2%, falling short of the 4% required for a lean. Similarly, the Guardians' increase in K-rate does not meet the criteria.

STEP 3: Report findings
No significant statistical edges meet our betting threshold in this matchup. Despite Daniel Schneemann's notable increase, his xBA does not surpass the .300 mark, and no team K-rate changes align with our criteria for a strikeout prop lean.

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