College Football game preview · Colorado Buffaloes vs Arizona State Sun Devils

Arizona State's Quarterback Change Meets Colorado's Road Slide in Tempe

Arizona State changed quarterbacks between its last two games, while Colorado has lost, failed to cover and gone over in three straight road games. With no team statistics, odds or betting splits in the sheet, the evidence is thin and mixed.

Key numbers

Spread (ASU)
-3.5
Total
48.5 opened 49
Moneyline
COLO +136 · ASU -163
Over bets / money
57% / 47%

Consensus across 27 sportsbooks.

Arizona State hosts Colorado on Saturday, November 7 at 7:30 PM ET in Tempe, and the evidence is thin enough that the quarterback situation and Colorado's recent road form carry most of the story. The only prior meeting in the sheet went to Arizona State, 42-17 at Colorado on 2025-11-23. That is one game from a different season, so it is context rather than a forecast.

The sharper question sits with the Sun Devils' passer. Arizona State changed quarterbacks between its last two games: Mikey Keene led the team with 20 pass attempts against the Kansas State Wildcats on 2026-10-24, and Jake Fette led with 42 attempts against the BYU Cougars on 2026-10-31. Fette has led in only 1 of the last 3 games, so his body of work as the starter is small. Behind him, Cardae Mack has 56 carries over the team's last 3 games, #1 among its running backs.

Colorado looks steadier at the position. Isaac Wilson led the team in pass attempts in 3 of its last 3 games, including 21 attempts against Kansas State on 2026-10-31. A headline from October 29 reported that Colorado quarterback Julian Lewis suffered a medical emergency and was hospitalized. That is a serious human story, but the injury tables show nothing reported for either team, and the report does not change who is listed as Colorado's starter. Joseph Williams has 19 receptions over the last 3 games, #1 among Colorado's wide receivers, and JaQuail Smith has 34 carries, #1 among its running backs.

Colorado's active streaks are the clearest tilt in the sheet, and they are descriptive only. The Buffaloes have lost 3 straight games on the road, failed to cover the spread in 3 straight road games, and gone over the total in 3 straight games overall. Together they describe a team that has been losing away from home in games that have still run high on points. The over streak is a record of past totals, not a read on this one, and none of it says whether the pattern continues in Tempe.

Conditions look benign: a forecast of 69°F, wind 3 mph NW and clear skies, which gives little reason to expect weather to affect the passing game or kicking. That removes one variable from a game in which the passing situations already carry uncertainty.

No team statistics, current odds or public betting splits are available, so there is no way here to compare the two sides' efficiency or to see how the price has moved. With that gap, the picture is mixed: Arizona State won the last meeting and Colorado's road results have been poor, but Arizona State is relying on a quarterback with a short run as its leading passer.

Colorado Buffaloes vs Arizona State Sun Devils: FAQ

When is Colorado Buffaloes vs Arizona State Sun Devils?

Colorado Buffaloes at Arizona State Sun Devils kicks off Saturday, November 7, 2026 at 7:30 PM ET.

Who is favored in Colorado Buffaloes vs Arizona State Sun Devils?

Arizona State Sun Devils is a 3.5-point favorite (consensus across 27 sportsbooks).

What is the over/under for Colorado Buffaloes vs Arizona State Sun Devils?

The consensus total is 48.5, after opening at 49.

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